He is an active soloist who has appeared at Civic Hall in Tokyo, the Embassy of the United States in Paris, Salle Pierre-Mercure in Montreal, and New York City's Merkin Concert Hall.

  Murphy's numerous awards and prizes include 2nd Prize in the Adolphe Sax International Saxophone Competition (1998), 3rd Prize in the Jean-Marie Londeix International Saxophone Competition (1996), 1st Prize in the Heida Hermanns Young Artist Competition, 2nd Prize in the St. Louis Symphony Young Artist Competition, and the J. William Fulbright grant that allowed saxophone study in France. In addition, he has been a finalist in the Concert Artists Guild and Pro Musicis competitions in New York City.

  His debut compact disc recording, Memories of Dinant, has received critical acclaim. Otis Murphy is a Yamaha Performing Artist and Clinician, actively performing recitals and giving clinics throughout the United States and abroad.